PMID:18227041

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Citation

Song, WB, Zhang, ZS and Xiao, B (2008) [Protective effect of curcumin against methotrexate-induced small intestinal damage in rats]. Nan Fang Yi Ke Da Xue Xue Bao 28:119-21

Abstract

To observe the changes in intestinal mucosal permeability in rats with methotrexate (MTX)-induced small intestinal damage and investigate the protective effects of curcumin.

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Keywords

Amine Oxidase (Copper-Containing)/metabolism; Animals; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Curcumin/pharmacology; Enteritis/chemically induced; Enteritis/pathology; Enteritis/prevention & control; Female; Immunohistochemistry; Intercellular Adhesion Molecule-1/metabolism; Intestinal Mucosa/drug effects; Intestinal Mucosa/metabolism; Intestinal Mucosa/pathology; Intestine, Small/drug effects; Intestine, Small/metabolism; Intestine, Small/pathology; Methotrexate; Peroxidase/metabolism; Rats; Rats, Sprague-Dawley; Spectrophotometry

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