PMID:18226777

Citation	Chess, DJ, Lei, B, Hoit, BD, Azimzadeh, AM and Stanley, WC (2008) Effects of a high saturated fat diet on cardiac hypertrophy and dysfunction in response to pressure overload. J. Card. Fail. 14:82-8
Abstract	Dietary lipid content effects activation of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and may accelerate cardiac hypertrophy and dysfunction in response to pressure overload. This study investigated the effects of a high-fat diet on the development of cardiac hypertrophy.
Links	PubMed PMC2702219 Online version:10.1016/j.cardfail.2007.09.004
Keywords	Animals; Blotting, Western; Cardiomyopathy, Hypertrophic/diet therapy; Cardiomyopathy, Hypertrophic/mortality; Cardiomyopathy, Hypertrophic/physiopathology; Chi-Square Distribution; Diet, Fat-Restricted; Dietary Fats/pharmacology; Disease Models, Animal; Fatty Acids, Nonesterified/metabolism; Fatty Acids, Nonesterified/pharmacology; Hypertension/metabolism; Hypertension/physiopathology; Mice; Mice, Inbred C57BL; Multivariate Analysis; PPAR alpha/genetics; PPAR alpha/metabolism; Probability; RNA, Messenger/analysis; Random Allocation; Reference Values; Risk Assessment; Sensitivity and Specificity; Stroke Volume/physiology; Survival Rate; Ventricular Dysfunction, Left/metabolism; Ventricular Dysfunction, Left/mortality; Ventricular Dysfunction, Left/physiopathology
edit table

Significance

You can help EcoliWiki by summarizing why this paper is useful

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Add links to pages that link here (e.g. gene, product, method pages)

See Help:References for how to manage references in EcoliWiki.