PMID:18226210

Citation	Björnerfeldt, S, Hailer, F, Nord, M and Vilà, C (2008) Assortative mating and fragmentation within dog breeds. BMC Evol. Biol. 8:28
Abstract	There are around 400 internationally recognized dog breeds in the world today, with a remarkable diversity in size, shape, color and behavior. Breeds are considered to be uniform groups with similar physical characteristics, shaped by selection rooted in human preferences. This has led to a large genetic difference between breeds and a large extent of linkage disequilibrium within breeds. These characteristics are important for association mapping of candidate genes for diseases and therefore make dogs ideal models for gene mapping of human disorders. However, genetic uniformity within breeds may not always be the case. We studied patterns of genetic diversity within 164 poodles and compared it to 133 dogs from eight other breeds.
Links	PubMed PMC2266708 Online version:10.1186/1471-2148-8-28
Keywords	Animals; Breeding/methods; Cluster Analysis; Dogs/classification; Dogs/genetics; Genetic Variation; Linkage Disequilibrium; Microsatellite Repeats/genetics; Pedigree
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