PMID:18226181
| Citation |
Ottaviani, D, Lever, E, Takousis, P and Sheer, D (2008) Anchoring the genome. Genome Biol. 9:201 |
|---|---|
| Abstract |
Although the principles governing chromosomal architecture are largely unresolved, there is evidence that higher-order chromatin folding is mediated by the anchoring of specific DNA sequences to the nuclear matrix. These genome anchors are also crucial regulators of gene expression and DNA replication, and play a role in pathogenesis. |
| Links |
PubMed PMC2395230 Online version:10.1186/gb-2008-9-1-201 |
| Keywords |
Binding Sites; Chromatin Assembly and Disassembly; DNA/metabolism; DNA Replication; Gene Expression Regulation; Genome; Nuclear Matrix/metabolism |
| edit table |
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