PMID:18225762
| Citation |
Khisamutdinova, RY, Zarudii, FS, Gabdrakhmanova, SF, Makara, NS, Baschenko, NZh and Nazarov, VS (2007) Effect of glialin on cardiac ventricular arrhythmias and myocardial conduction system in dogs. Bull. Exp. Biol. Med. 143:353-5 |
|---|---|
| Abstract |
Intravenous glialin in a dose of 7 mg/kg suppressed the number of ectopic contractions caused by double ligature of the left coronary artery by the method of Harris and almost 2-fold prolonged animal life-span in comparison with the control. The maximum antiarrhythmic effect of glialin developed after 180 min and persisted for 5 h. Glialin injected intravenously (10 mg/kg) after myocardial infarction under conditions of programmed electrical stimulation inhibited conduction of evoked impulse in the atria, Purkinje fibers, and ventricular myocardium and did not modify the effective refractory periods of the atria and ventricles. |
| Links | |
| Keywords |
Aconitine/administration & dosage; Aconitine/analogs & derivatives; Animals; Anti-Arrhythmia Agents/administration & dosage; Arrhythmias, Cardiac/drug therapy; Arrhythmias, Cardiac/physiopathology; Dogs; Electrophysiology; Glycyrrhizic Acid/administration & dosage; Heart Conduction System/drug effects; Heart Conduction System/physiopathology; Myocardial Infarction/drug therapy; Myocardial Infarction/physiopathology |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.