PMID:18217353

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Citation

Vrynchanu, NO [Antimicrobial effect of 4-(adamantyl-1)-1-(1-aminobutyl)benzol]. Mikrobiol. Z. 69:42-8

Abstract

Antimicrobial activity in vitro of adamantine derivative in respect of aerobic and anaerobic microorganisms has been studied. In these conditions Gram-positive bacteria and some representatives of Gram-negative microorganisms (Shigella flexneri, S. newvcastle, Enterobacter aerogenes etc.) had maximal sensitivity (MIC 0.6-5.0 and 0.1-5.0 mg/ml, respectively). Pseudomonas aeruginosa were resistant to this substance (MIC >1 mg/ml).

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Keywords

Adamantane/analogs & derivatives; Adamantane/pharmacology; Anti-Bacterial Agents/pharmacology; Gram-Negative Aerobic Bacteria/drug effects; Gram-Negative Anaerobic Bacteria/drug effects; Gram-Positive Cocci/drug effects; Gram-Positive Rods/drug effects; Microbial Sensitivity Tests

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