PMID:18215292
| Citation |
Vazquez, A, Beg, QK, Demenezes, MA, Ernst, J, Bar-Joseph, Z, Barabási, AL, Boros, LG and Oltvai, ZN (2008) Impact of the solvent capacity constraint on E. coli metabolism. BMC Syst Biol 2:7 |
|---|---|
| Abstract |
Obtaining quantitative predictions for cellular metabolic activities requires the identification and modeling of the physicochemical constraints that are relevant at physiological growth conditions. Molecular crowding in a cell's cytoplasm is one such potential constraint, as it limits the solvent capacity available to metabolic enzymes. |
| Links |
PubMed PMC2270259 Online version:10.1186/1752-0509-2-7 |
| Keywords |
Cell Size; Escherichia coli/cytology; Escherichia coli/enzymology; Escherichia coli/genetics; Escherichia coli/metabolism; Food; Gene Expression Regulation, Bacterial; Intracellular Space/metabolism; Models, Biological; Solvents |
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