PMID:18215272

Citation	Townsend, MK, Carr, NJ, Iyer, JG, Horne, SM, Gibbs, PS and Prüss, BM (2008) Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model. BMC Microbiol. 8:12
Abstract	The Yersinia enterocolitica flagellar master regulator FlhD/FlhC affects the expression levels of non-flagellar genes, including 21 genes that are involved in central metabolism. The sigma factor of the flagellar system, FliA, has a negative effect on the expression levels of seven plasmid-encoded virulence genes in addition to its positive effect on the expression levels of eight of the flagellar operons. This study investigates the phenotypes of flhD and fliA mutants that result from the complex gene regulation.
Links	PubMed PMC2262085 Online version:10.1186/1471-2180-8-12
Keywords	Animals; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Chick Embryo; Chickens; Flagella/genetics; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Models, Biological; Oligonucleotide Array Sequence Analysis/methods; Transcription, Genetic; Virulence/genetics; Yersinia enterocolitica/chemistry; Yersinia enterocolitica/genetics; Yersinia enterocolitica/pathogenicity
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