PMID:18165912

Citation	Juan, YS, Hydery, T, Mannikarottu, A, Kogan, B, Schuler, C, Leggett, RE, Lin, WY, Huang, CH and Levin, RM (2008) Coenzyme Q10 protect against ischemia/reperfusion induced biochemical and functional changes in rabbit urinary bladder. Mol. Cell. Biochem. 311:73-80
Abstract	Ischemia, reperfusion, and free radical generation have been recently implicated in the progressive bladder dysfunction. Coenzyme Q10 (CoQ10) is a pro-vitamin like substance that appears to be efficient for treatment of neurodegenerative disorders and ischemic heart disease. Our goal was to investigate the potential protective effect of CoQ10 in a rabbit model of in vivo bilateral ischemia and ischemia/reperfusion (I/R).
Links	PubMed Online version:10.1007/s11010-007-9696-y
Keywords	Animals; Antioxidants/administration & dosage; Antioxidants/pharmacology; Catalase/metabolism; Choline O-Acetyltransferase/metabolism; Citrate (si)-Synthase/metabolism; Dietary Supplements; Male; Mitochondria/metabolism; Muscle Contraction/drug effects; Rabbits; Reperfusion Injury/drug therapy; Reperfusion Injury/prevention & control; Superoxide Dismutase/metabolism; Ubiquinone/administration & dosage; Ubiquinone/analogs & derivatives; Ubiquinone/pharmacology; Ubiquinone/therapeutic use; Urinary Bladder/drug effects; Urinary Bladder/metabolism; Urinary Bladder/pathology
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