PMID:18090240
| Citation |
Hsiao, JY, Wang, CL, Hsia, PJ, Hsieh, MC, Hsin, SC, Lin, KD and Shin, SJ (2007) Decreased insulin secretion and insulin sensitivity are associated with liver function in subjects with fasting glucose between 100 and 109 mg/dL in Taiwanese population. Pancreas 35:343-7 |
|---|---|
| Abstract |
In 2003, the American Diabetes Association recommended that the lower limit for the diagnosis of impaired fasting glucose (IFG) should be reduced from 110 to 100 mg/dL in the analysis of the associated risk factors of IFG. It has been proposed that liver dysfunction may contribute to the development of type 2 diabetes. A primary aim was to investigate the relationship between liver enzyme and insulin resistance (IR) in IFG group. The secondary aim was to investigate IR and beta-cell function assessed by homeostasis model assessment (HOMA-IR and HOMA-%B, respectively) in subjects with fasting plasma glucose (FPG) between 100 and 109 mg/dL. |
| Links |
PubMed Online version:10.1097/mpa.0b013e31811f44fd |
| Keywords |
Adult; Alanine Transaminase/blood; Alkaline Phosphatase/blood; Aspartate Aminotransferases/blood; Blood Glucose/metabolism; Blood Pressure; Fasting/blood; Female; Glucose Tolerance Test; Hemoglobin A, Glycosylated/metabolism; Humans; Insulin/secretion; Insulin Resistance; Insulin-Secreting Cells/secretion; Lipids/blood; Liver Diseases/diagnosis; Liver Diseases/enzymology; Liver Diseases/metabolism; Liver Diseases/physiopathology; Liver Function Tests; Male; Middle Aged; Models, Biological; Taiwan; gamma-Glutamyltransferase/blood |
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