PMID:18078521

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Citation

Zaga-Clavellina, V, Garcia-Lopez, G, Flores-Herrera, H, Espejel-Nuñez, A, Flores-Pliego, A, Soriano-Becerril, D, Maida-Claros, R, Merchant-Larios, H and Vadillo-Ortega, F (2007) In vitro secretion profiles of interleukin (IL)-1beta, IL-6, IL-8, IL-10, and TNF alpha after selective infection with Escherichia coli in human fetal membranes. Reprod. Biol. Endocrinol. 5:46

Abstract

Chorioamniotic membranes infection is a pathologic condition in which an abnormal secretion of proinflammatory cytokines halts fetal immune tolerance. The aim of the present study was to evaluate the functional response of human chorioamniotic membranes, as well as the individual contribution of the amnion and choriodecidua after stimulation with Escherichia coli, a pathogen associated with preterm labor.

Links

PubMed PMC2175507 Online version:10.1186/1477-7827-5-46

Keywords

Adult; Escherichia coli; Escherichia coli Infections/metabolism; Extraembryonic Membranes/microbiology; Extraembryonic Membranes/secretion; Female; Humans; Interleukin-10/secretion; Interleukin-1beta/secretion; Interleukin-6/secretion; Interleukin-8/secretion; Models, Biological; Pregnancy; Tissue Culture Techniques; Tumor Necrosis Factor-alpha/secretion

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