PMID:18076183
| Citation |
Gramlich, PM, Wirges, CT, Gierlich, J and Carell, T (2008) Synthesis of modified DNA by PCR with alkyne-bearing purines followed by a click reaction. Org. Lett. 10:249-51 |
|---|---|
| Abstract |
Alkyne-bearing deazapurine triphosphates were prepared and successfully incorporated into DNA using the polymerase chain reaction (PCR). The obtained alkyne-labeled DNA was successfully used in a click reaction with galactose azide. |
| Links |
PubMed Online version:10.1021/ol7026015 |
| Keywords |
Azides/chemistry; DNA/chemistry; Galactose/analogs & derivatives; Galactose/chemistry; Molecular Structure; Polymerase Chain Reaction; Purine Nucleotides/chemical synthesis; Purine Nucleotides/chemistry |
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