PMID:18000553

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Citation

Blanchard, JL, Wholey, WY, Conlon, EM and Pomposiello, PJ (2007) Rapid changes in gene expression dynamics in response to superoxide reveal SoxRS-dependent and independent transcriptional networks. PLoS ONE 2:e1186

Abstract

SoxR and SoxS constitute an intracellular signal response system that rapidly detects changes in superoxide levels and modulates gene expression in E. coli. A time series microarray design was used to identify co-regulated SoxRS-dependent and independent genes modulated by superoxide minutes after exposure to stress.

Links

PubMed PMC2064960 Online version:10.1371/journal.pone.0001186

Keywords

Bacterial Proteins/genetics; Escherichia coli Proteins/genetics; Gene Expression; Paraquat/pharmacology; RNA, Messenger/genetics; Superoxides/metabolism; Trans-Activators/genetics; Transcription Factors/genetics; Transcription, Genetic/drug effects

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