PMID:17986320
| Citation |
Baumbach, J (2007) CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks. BMC Bioinformatics 8:429 |
|---|---|
| Abstract |
Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of microorganisms deduced from literature-derived knowledge, computer predictions and global DNA microarray hybridization experiments, has opened the way for the genome-wide analysis of transcriptional regulatory networks. The large-scale reconstruction of these networks allows the in silico analysis of cell behavior in response to changing environmental conditions. We previously published CoryneRegNet, an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. Initially, it was designed to provide methods for the analysis and visualization of the gene regulatory network of Corynebacterium glutamicum. |
| Links |
PubMed PMC2194740 Online version:10.1186/1471-2105-8-429 |
| Keywords |
Algorithms; Bacterial Proteins/metabolism; Corynebacterium glutamicum/metabolism; Database Management Systems; Databases, Protein; Gene Expression Regulation, Bacterial/physiology; Information Storage and Retrieval/methods; Reference Values; User-Computer Interface |
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CoryneRegNet
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