PMID:17933887
| Citation |
Abdallah, J, Caldas, T, Kthiri, F, Kern, R and Richarme, G (2007) YhbO protects cells against multiple stresses. J. Bacteriol. 189:9140-4 |
|---|---|
| Abstract |
YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is required for stress resistance. These results suggest that YhbO affects a central process in stress management. |
| Links |
PubMed PMC2168597 Online version:10.1128/JB.01208-07 |
| Keywords |
Anti-Bacterial Agents/pharmacology; Cysteine/genetics; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/physiology; Escherichia coli/radiation effects; Escherichia coli Proteins/genetics; Escherichia coli Proteins/physiology; Heat-Shock Proteins/genetics; Heat-Shock Proteins/physiology; Hot Temperature; Hydrogen-Ion Concentration; Mutagenesis, Insertional; Oxidants/pharmacology; Ultraviolet Rays |
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