PMID:17543094

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Citation

Oh, HY, Jin, X, Kim, JG, Oh, MJ, Pian, X, Kim, JM, Yoon, MS, Son, CI, Lee, YS, Hong, KC, Kim, H, Choi, YJ and Whang, KY (2007) Characteristics of primary and immortalized fibroblast cells derived from the miniature and domestic pigs. BMC Cell Biol. 8:20

Abstract

The pig, Sus scrofa domestica includes both the miniature and commercial domestic breed. These animals have influenced the human life and economies and have been studied throughout history. Although the miniature breeds are more recent and have increasingly been used in a variety of biomedical studies, their cell lines have rarely been established. Therefore, we sought to establish primary and immortal cell lines derived from both the miniature and domestic pig to better enable insight into possible in vivo growth differences.

Links

PubMed PMC1894962 Online version:10.1186/1471-2121-8-20

Keywords

Animals; Antigens, Polyomavirus Transforming/genetics; Cell Aging/physiology; Cell Line; Cell Proliferation; Cell Survival/physiology; Cells, Cultured; Chromosome Aberrations; Cyclin-Dependent Kinase Inhibitor p21/genetics; Cyclin-Dependent Kinase Inhibitor p21/physiology; Female; Fibroblasts/cytology; Fibroblasts/physiology; Phenotype; Signal Transduction; Sus scrofa; Swine; Swine, Miniature; Telomerase/genetics; Transduction, Genetic; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/physiology

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