PMID:17537821

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Citation

Okumura, T, Makiguchi, H, Makita, Y, Yamashita, R and Nakai, K (2007) Melina II: a web tool for comparisons among several predictive algorithms to find potential motifs from promoter regions. Nucleic Acids Res. 35:W227-31

Abstract

We present the second version of Melina, a web-based tool for promoter analysis. Melina II shows potential DNA motifs in promoter regions with a combination of several available programs, Consensus, MEME, Gibbs sampler, MDscan and Weeder, as well as several parameter settings. It allows running a maximum of four programs simultaneously, and comparing their results with graphical representations. In addition, users can build a weight matrix from a predicted motif and apply it to upstream sequences of several typical genomes (human, mouse, S. cerevisiae, E. coli, B. subtilis or A. thaliana) or to public motif databases (JASPAR or DBTBS) in order to find similar motifs. Melina II is a client/server system developed by using Adobe (Macromedia) Flash and is accessible over the web at http://melina.hgc.jp.

Links

PubMed PMC1933176 Online version:10.1093/nar/gkm362

Keywords

Algorithms; Amino Acid Motifs; Animals; Computational Biology/methods; Computer Graphics; Database Management Systems; Humans; Information Storage and Retrieval/methods; Internet; Promoter Regions, Genetic; Proteins/chemistry; Quality Control; Sequence Alignment/methods; Sequence Analysis, DNA/methods

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Melina
Category:Bioinformatics_Tools

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