PMID:17511876

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Citation

Lee, J, Jayaraman, A and Wood, TK (2007) Indole is an inter-species biofilm signal mediated by SdiA. BMC Microbiol. 7:42

Abstract

As a stationary phase signal, indole is secreted in large quantities into rich medium by Escherichia coli and has been shown to control several genes (e.g., astD, tnaB, gabT), multi-drug exporters, and the pathogenicity island of E. coli; however, its impact on biofilm formation has not been well-studied.

Links

PubMed PMC1899176 Online version:10.1186/1471-2180-7-42

Keywords

4-Butyrolactone/analogs & derivatives; 4-Butyrolactone/pharmacology; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Biofilms/drug effects; Biofilms/growth & development; Ecosystem; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/metabolism; Gene Expression Profiling; Gene Expression Regulation, Bacterial/drug effects; Genes, Bacterial; Indoles/chemistry; Indoles/metabolism; Indoles/pharmacology; Microbial Viability/drug effects; Molecular Structure; Mutation; Oligonucleotide Array Sequence Analysis; Pseudomonas/genetics; Pseudomonas/growth & development; Pseudomonas/metabolism; Trans-Activators/genetics; Trans-Activators/metabolism; Transcription, Genetic/drug effects; Tryptophan/metabolism

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