PMID:17472738

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Citation

Hammann, C and Westhof, E (2007) Searching genomes for ribozymes and riboswitches. Genome Biol. 8:210

Abstract

New regulatory RNAs with complex structures have recently been discovered, among them the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we discuss some of the experimental approaches and theoretical difficulties attached to the identification of new ribozymes in genomes.

Links

PubMed PMC1895996 Online version:10.1186/gb-2007-8-4-210

Keywords

Base Sequence; Computational Biology; Conserved Sequence; Genetic Variation; Genome; Genomics/methods; Nucleic Acid Conformation; RNA Splicing; RNA, Catalytic/chemistry; RNA, Catalytic/physiology; Regulatory Sequences, Ribonucleic Acid/physiology

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