PMID:17435004
| Citation |
Nie, Y, Xu, Y, Mu, XQ, Wang, HY, Yang, M and Xiao, R (2007) Purification, characterization, gene cloning, and expression of a novel alcohol dehydrogenase with anti-prelog stereospecificity from Candida parapsilosis. Appl. Environ. Microbiol. 73:3759-64 |
|---|---|
| Abstract |
An alcohol dehydrogenase from Candida parapsilosis CCTCC M203011 was characterized along with its biochemical activity and structural gene. The amino acid sequence shows similarity to those of the short-chain dehydrogenase/reductases but no overall identity to known proteins. This enzyme with unusual stereospecificity catalyzes an anti-Prelog reduction of 2-hydroxyacetophenone to (S)-1-phenyl-1,2-ethanediol. |
| Links |
PubMed PMC1932682 Online version:10.1128/AEM.02185-06 |
| Keywords |
Alcohol Dehydrogenase/genetics; Alcohol Dehydrogenase/metabolism; Amino Acid Sequence; Candida/enzymology; Candida/genetics; Candida/metabolism; Cloning, Molecular; DNA, Fungal/chemistry; DNA, Fungal/genetics; Hydrogen-Ion Concentration; Molecular Sequence Data; Sequence Alignment; Sequence Analysis, DNA; Stereoisomerism; Substrate Specificity |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.