PMID:17428339

Citation	Till, BJ, Cooper, J, Tai, TH, Colowit, P, Greene, EA, Henikoff, S and Comai, L (2007) Discovery of chemically induced mutations in rice by TILLING. BMC Plant Biol. 7:19
Abstract	Rice is both a food source for a majority of the world's population and an important model system. Available functional genomics resources include targeted insertion mutagenesis and transgenic tools. While these can be powerful, a non-transgenic, unbiased targeted mutagenesis method that can generate a range of allele types would add considerably to the analysis of the rice genome. TILLING (Targeting Induced Local Lesions in Genomes), a general reverse genetic technique that combines traditional mutagenesis with high throughput methods for mutation discovery, is such a method.
Links	PubMed PMC1858691 Online version:10.1186/1471-2229-7-19
Keywords	Agriculture; DNA, Plant/genetics; DNA, Plant/isolation & purification; Ethyl Methanesulfonate/pharmacology; Methylnitrosourea/pharmacology; Mutagenesis; Mutagens/pharmacology; Mutation; Oryza sativa/drug effects; Oryza sativa/genetics; Sodium Azide/pharmacology
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