PMID:1722255
| Citation |
Henry, MF and Cronan, JE Jr (1991) Escherichia coli transcription factor that both activates fatty acid synthesis and represses fatty acid degradation. J. Mol. Biol. 222:843-9 |
|---|---|
| Abstract |
The fadR gene of Escherichia coli encodes a protein that acts as a negative regulator (repressor) of the inducible beta-oxidation pathway. We report that the FadR protein also functions as a positive transcriptional activator of the fabA gene, which encodes the enzyme introducing the double bond of the unsaturated fatty acids of E. coli. |
| Links | |
| Keywords |
Bacterial Proteins; Blotting, Northern; Cloning, Molecular; DNA-Binding Proteins/genetics; Escherichia coli/genetics; Escherichia coli/metabolism; Fatty Acids/biosynthesis; Fatty Acids/metabolism; Genes, Bacterial; RNA, Bacterial/genetics; RNA, Bacterial/isolation & purification; Repressor Proteins/genetics; Repressor Proteins/metabolism; Restriction Mapping; Transcription, Genetic |
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