PMID:17189366
| Citation |
Weiss, B (2007) YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12. J. Bacteriol. 189:2186-9 |
|---|---|
| Abstract |
Exogenous thymine must be converted to thymidine to enable a thyA (thymidylate synthase) mutant to grow. The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium. |
| Links |
PubMed PMC1855703 Online version:10.1128/JB.01645-06 |
| Keywords |
Deoxyuracil Nucleotides/metabolism; Escherichia coli/metabolism; Escherichia coli Proteins/physiology; N-Glycosyl Hydrolases/physiology; Phosphorylation; Thymidylate Synthase/physiology; Thymine/metabolism |
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