PMID:16953894

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Citation

Karpinets, TV, Greenwood, DJ, Sams, CE and Ammons, JT (2006) RNA:protein ratio of the unicellular organism as a characteristic of phosphorous and nitrogen stoichiometry and of the cellular requirement of ribosomes for protein synthesis. BMC Biol. 4:30

Abstract

Mean phosphorous:nitrogen (P:N) ratios and relationships of P:N ratios with the growth rate of organisms indicate a surprising similarity among and within microbial species, plants, and insect herbivores. To reveal the cellular mechanisms underling this similarity, the macromolecular composition of seven microorganisms and the effect of specific growth rate (SGR) on RNA:protein ratio, the number of ribosomes, and peptide elongation rate (PER) were analyzed under different conditions of exponential growth.

Links

PubMed PMC1574349 Online version:10.1186/1741-7007-4-30

Keywords

Escherichia coli/physiology; Models, Biological; Mycobacterium bovis/physiology; Neurospora crassa/physiology; Nitrogen/chemistry; Phosphorus/chemistry; Protein Biosynthesis; Prototheca/physiology; RNA/chemistry; Ribosomes/chemistry; Saccharomyces cerevisiae/physiology; Selenomonas/physiology; Streptomyces coelicolor/physiology

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