PMID:16923914
| Citation |
Gulmezian, M, Zhang, H, Javor, GT and Clarke, CF (2006) Genetic evidence for an interaction of the UbiG O-methyltransferase with UbiX in Escherichia coli coenzyme Q biosynthesis. J. Bacteriol. 188:6435-9 |
|---|---|
| Abstract |
IS16 is a thiol-sensitive, Q-deficient mutant strain of Escherichia coli. Here, we show that IS16 harbors a mutation in the ubiG gene encoding a methyltransferase required for two O-methylation steps of Q biosynthesis. Complementation of IS16 with either ubiG or ubiX(K-12) reverses this phenotype, suggesting that UbiX may interact with UbiG. |
| Links |
PubMed PMC1595381 Online version:10.1128/JB.00668-06 |
| Keywords |
Carboxy-Lyases/metabolism; Escherichia coli/enzymology; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Genetic Complementation Test; Methylation; Methyltransferases/genetics; Methyltransferases/metabolism; Mutation; Sequence Alignment; Ubiquinone/biosynthesis |
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