PMID:1675635
| Citation |
Muday, GK, Johnson, DI, Somerville, RL and Herrmann, KM (1991) The tyrosine repressor negatively regulates aroH expression in Escherichia coli. J. Bacteriol. 173:3930-2 |
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| Abstract |
The levels of the tryptophan-sensitive isoenzyme of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of Escherichia coli, encoded by the aroH gene, were elevated in tyrR and/or trpR mutants. The effect of tyrR and trpR lesions on aroH expression was confirmed by using a lacZ reporter system. The mutational elimination of either repressor led to a threefold increase in beta-galactosidase. |
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| Keywords |
3-Deoxy-7-Phosphoheptulonate Synthase/genetics; Base Sequence; Escherichia coli/enzymology; Escherichia coli/genetics; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Isoenzymes/genetics; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid; Repressor Proteins/genetics; Tyrosine; beta-Galactosidase/analysis |
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