PMID:16603075
| Citation |
Pacifico, S, Liu, G, Guest, S, Parrish, JR, Fotouhi, F and Finley, RL Jr (2006) A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila. BMC Bioinformatics 7:195 |
|---|---|
| Abstract |
Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of interaction data derived from both experimental and computational techniques for a number of organisms. The volume of this data combined with the variety of specific forms it can take has created a need for comprehensive databases that include all of the available data sets, and for exploration tools to facilitate data integration and analysis. One powerful paradigm for the navigation and analysis of interaction data is an interaction graph or map that represents proteins or genes as nodes linked by interactions. Several programs have been developed for graphical representation and analysis of interaction data, yet there remains a need for alternative programs that can provide casual users with rapid easy access to many existing and emerging data sets. |
| Links |
PubMed PMC1458360 Online version:10.1186/1471-2105-7-195 |
| Keywords |
Database Management Systems; Databases, Genetic; Drosophila Proteins/genetics; Drosophila Proteins/metabolism; Gene Expression Profiling/methods; Information Storage and Retrieval/methods; Internet; Protein Interaction Mapping/methods; Software; Systems Integration; User-Computer Interface |
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