PMID:16451192

Citation	Elgrably-Weiss, M, Schlosser-Silverman, E, Rosenshine, I and Altuvia, S (2006) DeoT, a DeoR-type transcriptional regulator of multiple target genes. FEMS Microbiol. Lett. 254:141-8
Abstract	In this study, we investigated the genetic organization and function of Escherichia coli yciT, a gene predicted by computational methods to belong to the DeoR-type family of transcriptional regulators. We show that transcription of yciT (here denoted deoT for deoR-Type) initiates from a promoter located upstream of a putative open reading frame (denoted deoL for deoT Leader). We also show that DeoT acts as a global regulator, repressing the expression of a number of genes involved in a variety of metabolic pathways including transport of maltose, fatty acid beta-oxidation and peptide degradation.
Links	PubMed Online version:10.1111/j.1574-6968.2005.00020.x
Keywords	Base Sequence; DNA-Binding Proteins/chemistry; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Repressor Proteins/chemistry; Repressor Proteins/genetics; Repressor Proteins/metabolism; Transcription, Genetic
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