PMID:16356716

Citation	Ragan, MA, Harlow, TJ and Beiko, RG (2006) Do different surrogate methods detect lateral genetic transfer events of different relative ages? Trends Microbiol. 14:4-8
Abstract	Non-tree-based ("surrogate") methods have been used to identify instances of lateral genetic transfer in microbial genomes but agreement among predictions of different methods can be poor. It has been proposed that this disagreement arises because different surrogate methods are biased towards the detection of certain types of transfer events. This conjecture is supported by a rigorous phylogenetic analysis of 3776 proteins in Escherichia coli K12 MG1655 to map the ages of transfer events relative to one another.
Links	PubMed Online version:10.1016/j.tim.2005.11.004
Keywords	Base Composition; Computational Biology; Escherichia coli K12/genetics; Escherichia coli Proteins/genetics; Gene Transfer, Horizontal/genetics; Genome, Bacterial/genetics; Markov Chains; Phylogeny
edit table

Significance

You can help EcoliWiki by summarizing why this paper is useful

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Add links to pages that link here (e.g. gene, product, method pages)

See Help:References for how to manage references in EcoliWiki.