PMID:16166550

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Citation

Nouwen, N and Driessen, AJ (2005) Inactivation of protein translocation by cold-sensitive mutations in the yajC-secDF operon. J. Bacteriol. 187:6852-5

Abstract

Most mutations in the yajC-secDF operon identified via genetic screens confer a cold-sensitive growth phenotype. Here we report that two of these mutations confer this cold-sensitive phenotype by inactivating the SecDF-YajC complex in protein translocation.

Links

PubMed PMC1251580 Online version:10.1128/JB.187.19.6852-6855.2005

Keywords

Amino Acid Sequence; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Cold Temperature; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Expression Regulation, Bacterial; Intracellular Membranes/metabolism; Membrane Proteins/genetics; Membrane Proteins/metabolism; Membrane Transport Proteins/genetics; Membrane Transport Proteins/metabolism; Molecular Sequence Data; Mutation; Operon/physiology

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