PMID:16153292
| Citation |
Stancek, M, Schnell, R and Rydén-Aulin, M (2005) Analysis of Escherichia coli nicotinate mononucleotide adenylyltransferase mutants in vivo and in vitro. BMC Biochem. 6:16 |
|---|---|
| Abstract |
Adenylation of nicotinate mononucleotide to nicotinate adenine dinucleotide is the penultimate step in NAD+ synthesis. In Escherichia coli, the enzyme nicotinate mononucleotide adenylyltransferase is encoded by the nadD gene. We have earlier made an initial characterization in vivo of two mutant enzymes, NadD72 and NadD74. Strains with either mutation have decreased intracellular levels of NAD+, especially for one of the alleles, nadD72. |
| Links |
PubMed PMC1249556 Online version:10.1186/1471-2091-6-16 |
| Keywords |
Binding Sites/physiology; Escherichia coli/enzymology; Escherichia coli/genetics; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Mutation; Nicotinamide-Nucleotide Adenylyltransferase/chemistry; Nicotinamide-Nucleotide Adenylyltransferase/genetics; Nicotinamide-Nucleotide Adenylyltransferase/metabolism; Protein Conformation |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.
