PMID:16077136

Citation	Nouwen, N, Piwowarek, M, Berrelkamp, G and Driessen, AJ (2005) The large first periplasmic loop of SecD and SecF plays an important role in SecDF functioning. J. Bacteriol. 187:5857-60
Abstract	A remarkable feature of proteins of the SecD and SecF family involved in protein translocation is that they possess a very large first periplasmic domain. Here we report that this large first periplasmic domain is not required for the SecD-SecF interaction but that it is important for catalyzing protein translocation.
Links	PubMed PMC1196081 Online version:10.1128/JB.187.16.5857-5860.2005
Keywords	Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Cytoplasm/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins/chemistry; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Deletion; Membrane Proteins/chemistry; Membrane Proteins/genetics; Membrane Proteins/metabolism; Membrane Transport Proteins/chemistry; Membrane Transport Proteins/genetics; Membrane Transport Proteins/metabolism; Mutagenesis; Protein Structure, Tertiary
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