PMID:16040624

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Citation

Enne, VI, Delsol, AA, Davis, GR, Hayward, SL, Roe, JM and Bennett, PM (2005) Assessment of the fitness impacts on Escherichia coli of acquisition of antibiotic resistance genes encoded by different types of genetic element. J. Antimicrob. Chemother. 56:544-51

Abstract

Little is known of the fitness cost that antibiotic resistance exerts on wild-type bacteria, especially in their natural environments. We therefore examined the fitness costs that several antibiotic resistance elements imposed on a wild-type Escherichia coli isolate, both in the laboratory and in a pig gut colonization model.

Links

PubMed Online version:10.1093/jac/dki255

Keywords

Animals; Anti-Bacterial Agents/pharmacology; Biological Evolution; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial/genetics; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/pathogenicity; Escherichia coli Proteins; Feces/microbiology; Gastrointestinal Tract/microbiology; Plasmids/genetics; Ribosomal Proteins/drug effects; Ribosomal Proteins/genetics; Streptomycin/pharmacology; Swine; Swine Diseases/microbiology

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