PMID:15985496

Citation	Pinter, RY, Rokhlenko, O, Yeger-Lotem, E and Ziv-Ukelson, M (2005) Alignment of metabolic pathways. Bioinformatics 21:3401-8
Abstract	Several genome-scale efforts are underway to reconstruct metabolic networks for a variety of organisms. As the resulting data accumulates, the need for analysis tools increases. A notable requirement is a pathway alignment finder that enables both the detection of conserved metabolic pathways among different species as well as divergent metabolic pathways within a species. When comparing two pathways, the tool should be powerful enough to take into account both the pathway topology as well as the nodes' labels (e.g. the enzymes they denote), and allow flexibility by matching similar--rather than identical--pathways.
Links	PubMed Online version:10.1093/bioinformatics/bti554
Keywords	Animals; Gene Expression Regulation/physiology; Humans; Metabolism/physiology; Models, Biological; Multienzyme Complexes/metabolism; Pattern Recognition, Automated/methods; Signal Transduction/physiology; Species Specificity
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