PMID:15850456
| Citation |
Saparov, SM, Tsunoda, SP and Pohl, P (2005) Proton exclusion by an aquaglyceroprotein: a voltage clamp study. Biol. Cell 97:545-50 |
|---|---|
| Abstract |
In silico both orthodox aquaporins and aquaglyceroporins are shown to exclude protons. Supporting experimental evidence is available only for orthodox aquaporins. In contrast, the subset of the aquaporin water channel family that is permeable to glycerol and certain small, uncharged solutes has not yet been shown to exclude protons. Moreover, different aquaglyceroporins have been reported to conduct ions when reconstituted in planar bilayers. |
| Links |
PubMed Online version:10.1042/BC20040136 |
| Keywords |
Aquaporins/metabolism; Cell Membrane Permeability; Escherichia coli Proteins/metabolism; Glycerol/metabolism; Lipid Bilayers/chemistry; Membrane Proteins/chemistry; Patch-Clamp Techniques; Permeability; Protons; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/metabolism; Water/metabolism |
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