PMID:15838058
| Citation |
Boulanger, A, Francez-Charlot, A, Conter, A, Castanié-Cornet, MP, Cam, K and Gutierrez, C (2005) Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay. J. Bacteriol. 187:3282-6 |
|---|---|
| Abstract |
Transcription of the Escherichia coli osmB gene is induced by several stress conditions. osmB is expressed from two promoters, osmBp1 and osmBp2. The downstream promoter, osmBp2, is induced after osmotic shock or upon entry into stationary phase in a sigma(S)-dependent manner. The upstream promoter, osmBp1, is independent of sigma(S) and is activated by RcsB, the response regulator of the His-Asp phosphorelay signal transduction system RcsCDB. RcsB is responsible for the induction of osmBp1 following treatment with chlorpromazine. Activation of osmBp1 by RcsB requires a sequence upstream of its -35 element similar to the RcsB binding site consensus, suggesting a direct regulatory role. osmB appears as another example of a multistress-responsive gene whose transcription involves both a sigma(S)-dependent promoter and a second one independent of sigma(S) but controlled by stress-specific transcription factors. |
| Links |
PubMed PMC1082829 Online version:10.1128/JB.187.9.3282-3286.2005 |
| Keywords |
Adaptation, Physiological; Aspartic Acid/metabolism; Bacterial Outer Membrane Proteins/biosynthesis; Bacterial Outer Membrane Proteins/genetics; Bacterial Proteins/metabolism; Base Sequence; DNA, Bacterial; Escherichia coli/growth & development; Escherichia coli/physiology; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Escherichia coli Proteins/physiology; Gene Expression Regulation, Bacterial; Histidine/metabolism; Lipoproteins/biosynthesis; Lipoproteins/genetics; Molecular Sequence Data; Periplasmic Proteins/biosynthesis; Periplasmic Proteins/genetics; Promoter Regions, Genetic; Sigma Factor/metabolism; Signal Transduction; Transcription Factors/metabolism |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.