PMID:15838054

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Citation

Wang, A and Crowley, DE (2005) Global gene expression responses to cadmium toxicity in Escherichia coli. J. Bacteriol. 187:3259-66

Abstract

Genome-wide analysis of temporal gene expression profiles in Escherichia coli following exposure to cadmium revealed a shift to anaerobic metabolism and induction of several stress response systems. Disruption in the transcription of genes encoding ribosomal proteins and zinc-binding proteins may partially explain the molecular mechanisms of cadmium toxicity.

Links

PubMed PMC1082819 Online version:10.1128/JB.187.9.3259-3266.2005

Keywords

Adaptation, Physiological; Biological Transport; Cadmium/pharmacology; Carrier Proteins/genetics; Coliphages; DNA Transposable Elements; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli Proteins/genetics; Gene Expression Regulation, Bacterial; Oligonucleotide Array Sequence Analysis; Plasmids; Protein Processing, Post-Translational; Ribosomal Proteins/genetics

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