PMID:15716374

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Citation

Howard, M and Kruse, K (2005) Cellular organization by self-organization: mechanisms and models for Min protein dynamics. J. Cell Biol. 168:533-6

Abstract

We use the oscillating Min proteins of Escherichia coli as a prototype system to illustrate the current state and potential of modeling protein dynamics in space and time. We demonstrate how a theoretical approach has led to striking new insights into the mechanisms of self-organization in bacterial cells and indicate how these ideas may be applicable to more complex structure formation in eukaryotic cells.

Links

PubMed PMC2171746 Online version:10.1083/jcb.200411122

Keywords

Adenosine Triphosphatases/metabolism; Biological Clocks/physiology; Cell Cycle Proteins; Cell Division/physiology; Cytoskeleton/physiology; Escherichia coli/cytology; Escherichia coli/physiology; Escherichia coli Proteins/metabolism; Models, Biological; Protein Binding

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