PMID:15691972

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Citation

Shimizu, K, Hayashi, S, Kako, T, Suzuki, M, Tsukagoshi, N, Doukyu, N, Kobayashi, T and Honda, H (2005) Discovery of glpC, an organic solvent tolerance-related gene in Escherichia coli, using gene expression profiles from DNA microarrays. Appl. Environ. Microbiol. 71:1093-6

Abstract

Gene expression profiles were collected from Escherichia coli strains (OST3410, TK33, and TK31) before and after exposure to organic solvents, and the six genes that showed higher gene expression were selected. Among these genes, glpC encoding the anaerobic glycerol-3-phosphate dehydrogenase subunit C remarkably increased the organic solvent tolerance.

Links

PubMed PMC546683 Online version:10.1128/AEM.71.2.1093-1096.2005

Keywords

Cyclohexanes/pharmacology; Escherichia coli K12/drug effects; Escherichia coli K12/genetics; Escherichia coli K12/growth & development; Escherichia coli K12/metabolism; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Glycerolphosphate Dehydrogenase/genetics; Glycerolphosphate Dehydrogenase/metabolism; Oligonucleotide Array Sequence Analysis/methods; Solvents/pharmacology; Xylenes/pharmacology

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