PMID:15687217

Citation	Pérez-Capilla, T, Baquero, MR, Gómez-Gómez, JM, Ionel, A, Martín, S and Blázquez, J (2005) SOS-independent induction of dinB transcription by beta-lactam-mediated inhibition of cell wall synthesis in Escherichia coli. J. Bacteriol. 187:1515-8
Abstract	Transcription of the dinB gene, encoding DNA polymerase IV, is induced by the inhibition of cell wall synthesis at different levels. Using the beta-lactam antibiotic ceftazidime, a PBP3 inhibitor, as a model, we have shown that this induction is independent of the LexA/RecA regulatory system. Induction of dinB transcription mediated by ceftazidime produces an increase in the reversion of a +1 Lac frameshift mutation.
Links	PubMed PMC545630 Online version:10.1128/JB.187.4.1515-1518.2005
Keywords	Adenosine Triphosphatases/physiology; Bacterial Proteins/physiology; Ceftazidime/pharmacology; Cell Wall/metabolism; DNA Helicases/physiology; Enzyme Inhibitors/pharmacology; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins/genetics; Frameshift Mutation; Gene Expression Regulation, Bacterial/drug effects; SOS Response (Genetics); Serine Endopeptidases/physiology; Transcription, Genetic; beta-Galactosidase/analysis; beta-Galactosidase/genetics
edit table

Significance

You can help EcoliWiki by summarizing why this paper is useful

You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.

Add links to pages that link here (e.g. gene, product, method pages)

See Help:References for how to manage references in EcoliWiki.