PMID:15625857

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Citation

Stein, JP Jr and Bloch, KE (1976) Inhibition of E. coli beta-hydroxydecanoyl thioester dehydrase by ppGpp. Biochem. Biophys. Res. Commun. 73:881-4

Abstract

Guanosine-5'-diphosphate-3'-diphosphate was found to inhibit beta-hydroxydecanoyl thioester dehydrase of E. coli at concentrations corresponding to those generated in vivo during amino acid starvation of rel+ cells.

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Keywords

Enzyme Inhibitors/pharmacology; Escherichia coli/enzymology; Fatty Acid Synthetase Complex, Type II; Guanosine Tetraphosphate/pharmacology; Hydro-Lyases/antagonists & inhibitors; Hydro-Lyases/metabolism

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