PMID:15572476

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Citation

Rahman, SA, Advani, P, Schunk, R, Schrader, R and Schomburg, D (2005) Metabolic pathway analysis web service (Pathway Hunter Tool at CUBIC). Bioinformatics 21:1189-93

Abstract

Pathway Hunter Tool (PHT), is a fast, robust and user-friendly tool to analyse the shortest paths in metabolic pathways. The user can perform shortest path analysis for one or more organisms or can build virtual organisms (networks) using enzymes. Using PHT, the user can also calculate the average shortest path (Jungnickel, 2002 Graphs, Network and Algorithm. Springer-Verlag, Berlin), average alternate path and the top 10 hubs in the metabolic network. The comparative study of metabolic connectivity and observing the cross talk between metabolic pathways among various sequenced genomes is possible.

Links

PubMed Online version:10.1093/bioinformatics/bti116

Keywords

Algorithms; Computer Simulation; Databases, Factual; Energy Metabolism/physiology; Escherichia coli/metabolism; Escherichia coli Proteins/metabolism; Gene Expression Profiling/methods; Gene Expression Regulation/physiology; Internet; Models, Biological; Protein Interaction Mapping/methods; Signal Transduction/physiology; Software; Transcription Factors/metabolism

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