PMID:15564303

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Citation

Jacob, E, Sasikumar, R and Nair, KN (2005) A fuzzy guided genetic algorithm for operon prediction. Bioinformatics 21:1403-7

Abstract

The operon structure of the prokaryotic genome is a critical input for the reconstruction of regulatory networks at the whole genome level. As experimental methods for the detection of operons are difficult and time-consuming, efforts are being put into developing computational methods that can use available biological information to predict operons.

Links

PubMed Online version:10.1093/bioinformatics/bti156

Keywords

Algorithms; Bacillus subtilis/genetics; Bacterial Proteins/genetics; Chromosome Mapping/methods; Escherichia coli/genetics; Fuzzy Logic; Gene Expression Regulation, Bacterial/genetics; Models, Genetic; Models, Statistical; Operon/genetics; Sequence Alignment/methods; Sequence Analysis, DNA/methods; Signal Transduction/genetics

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