PMID:15551273

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Citation

Smith, KC (2004) Recombinational DNA repair: the ignored repair systems. Bioessays 26:1322-6

Abstract

The recent finding of a role for the recA gene in DNA replication restart does not negate previous data showing the existence of recA-dependent recombinational DNA repair, which occurs when there are two DNA duplexes present, as in the case for recA-dependent excision repair, for postreplication repair (i.e., the repair of DNA daughter-strand gaps), and for the repair of DNA double-strand breaks. Recombinational DNA repair is critical for the survival of damaged cells.

Links

PubMed Online version:10.1002/bies.20109

Keywords

Bacterial Proteins/metabolism; DNA/metabolism; DNA/radiation effects; DNA Repair; DNA-Binding Proteins/metabolism; DNA-Directed DNA Polymerase; Escherichia coli Proteins/metabolism; Rec A Recombinases/metabolism; Recombination, Genetic; Ultraviolet Rays

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