PMID:15539452

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Citation

Urbanczik, R and Wagner, C (2005) An improved algorithm for stoichiometric network analysis: theory and applications. Bioinformatics 21:1203-10

Abstract

Genome scale analysis of the metabolic network of a microorganism is a major challenge in bioinformatics. The combinatorial explosion, which occurs during the construction of elementary fluxes (non-redundant pathways) requires sophisticated and efficient algorithms to tackle the problem.

Links

PubMed Online version:10.1093/bioinformatics/bti127

Keywords

Algorithms; Combinatorial Chemistry Techniques; Computer Simulation; Databases, Factual; Energy Metabolism/physiology; Escherichia coli/physiology; Escherichia coli Proteins/metabolism; Gene Expression Profiling/methods; Gene Expression Regulation, Bacterial/physiology; Models, Biological; Protein Interaction Mapping/methods; Signal Transduction/physiology; Transcription Factors/metabolism

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