PMID:15509602

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Citation

Sabatti, C, Rohlin, L, Lange, K and Liao, JC (2005) Vocabulon: a dictionary model approach for reconstruction and localization of transcription factor binding sites. Bioinformatics 21:922-31

Abstract

Gene expression arrays enable measurements of transcription values for a large number or all genes in the genome. In order to better interpret these results and to use them to reconstruct transcription networks, information on location of binding sites for regulatory proteins in the entire genome is needed. In particular, this represents an open problem in Escherichia coli.

Links

PubMed Online version:10.1093/bioinformatics/bti083

Keywords

Algorithms; Binding Sites; Models, Chemical; Models, Genetic; Models, Statistical; Protein Binding; Sequence Alignment/methods; Sequence Analysis, DNA/methods; Software; Transcription Factors/chemistry; Transcription Factors/genetics; Transcription Factors/metabolism

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