PMID:15364957

Citation	Dalbey, RE and Kuhn, A (2004) YidC family members are involved in the membrane insertion, lateral integration, folding, and assembly of membrane proteins. J. Cell Biol. 166:769-74
Abstract	Members of the YidC family exist in all three domains of life, where they control the assembly of a large variety of membrane protein complexes that function as transporters, energy devices, or sensor proteins. Recent studies in bacteria have shown that YidC functions on its own as a membrane protein insertase independent of the Sec protein-conducting channel. YidC can also assist in the lateral integration and folding of membrane proteins that insert into the membrane via the Sec pathway.
Links	PubMed PMC2172118 Online version:10.1083/jcb.200405161
Keywords	Animals; Bacterial Proteins/chemistry; Bacterial Proteins/metabolism; Escherichia coli Proteins/metabolism; Humans; Membrane Proteins/chemistry; Membrane Proteins/metabolism; Membrane Transport Proteins/metabolism; Membrane Transport Proteins/physiology; Models, Biological; Protein Folding; Protein Precursors/metabolism; Substrate Specificity
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