PMID:14734314
| Citation |
Klamt, S and Gilles, ED (2004) Minimal cut sets in biochemical reaction networks. Bioinformatics 20:226-34 |
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| Abstract |
Structural studies of metabolic networks yield deeper insight into topology, functionality and capabilities of the metabolisms of different organisms. Here, we address the analysis of potential failure modes in metabolic networks whose occurrence will render the network structurally incapable of performing certain functions. Such studies will help to identify crucial parts in the network structure and to find suitable targets for repressing undesired metabolic functions. |
| Links | |
| Keywords |
Algorithms; Biochemistry/methods; Cell Physiological Phenomena; Computer Simulation; Escherichia coli/growth & development; Escherichia coli/metabolism; Metabolism/physiology; Models, Biological; Multienzyme Complexes/physiology; Signal Transduction/physiology |
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