PMID:14671304
| Citation |
Methé, BA, Nelson, KE, Eisen, JA, Paulsen, IT, Nelson, W, Heidelberg, JF, Wu, D, Wu, M, Ward, N, Beanan, MJ, Dodson, RJ, Madupu, R, Brinkac, LM, Daugherty, SC, DeBoy, RT, Durkin, AS, Gwinn, M, Kolonay, JF, Sullivan, SA, Haft, DH, Selengut, J, Davidsen, TM, Zafar, N, White, O, Tran, B, Romero, C, Forberger, HA, Weidman, J, Khouri, H, Feldblyum, TV, Utterback, TR, Van Aken, SE, Lovley, DR and Fraser, CM (2003) Genome of Geobacter sulfurreducens: metal reduction in subsurface environments. Science 302:1967-9 |
|---|---|
| Abstract |
The complete genome sequence of Geobacter sulfurreducens, a delta-proteobacterium, reveals unsuspected capabilities, including evidence of aerobic metabolism, one-carbon and complex carbon metabolism, motility, and chemotactic behavior. These characteristics, coupled with the possession of many two-component sensors and many c-type cytochromes, reveal an ability to create alternative, redundant, electron transport networks and offer insights into the process of metal ion reduction in subsurface environments. As well as playing roles in the global cycling of metals and carbon, this organism clearly has the potential for use in bioremediation of radioactive metals and in the generation of electricity. |
| Links |
PubMed Online version:10.1126/science.1088727 |
| Keywords |
Acetates/metabolism; Acetyl Coenzyme A/metabolism; Aerobiosis; Anaerobiosis; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Carbon/metabolism; Chemotaxis; Chromosomes, Bacterial/genetics; Cytochromes c/genetics; Cytochromes c/metabolism; Electron Transport; Energy Metabolism; Genes, Bacterial; Genes, Regulator; Genome, Bacterial; Geobacter/genetics; Geobacter/metabolism; Geobacter/physiology; Hydrogen/metabolism; Metals/metabolism; Movement; Open Reading Frames; Oxidation-Reduction; Phylogeny |
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