PMID:14667252
| Citation |
Kurowski, MA, Bhagwat, AS, Papaj, G and Bujnicki, JM (2003) Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB. BMC Genomics 4:48 |
|---|---|
| Abstract |
Combination of biochemical and bioinformatic analyses led to the discovery of oxidative demethylation - a novel DNA repair mechanism catalyzed by the Escherichia coli AlkB protein and its two human homologs, hABH2 and hABH3. This discovery was based on the prediction made by Aravind and Koonin that AlkB is a member of the 2OG-Fe2+ oxygenase superfamily. |
| Links |
PubMed PMC317286 Online version:10.1186/1471-2164-4-48 |
| Keywords |
Amino Acid Sequence; DNA Repair; Databases, Genetic; Genome, Human; Humans; Mixed Function Oxygenases/genetics; Molecular Sequence Data; Multigene Family/genetics; Phylogeny; Sequence Alignment; Sequence Homology, Amino Acid |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.